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Rare Chemicals
- Protein Control Ligand
- Pathway Inhibitors
- Enzyme Inhibitors
- Kinase Inhibitors
- Protease
- Synthase
- p18
- p38
- p53
- p70
- p90
- Peptidase
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- Cell Inhibition
- Synthase
- Receptor Tyrosine Phosphatases (RTP)
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- Autophagy
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- Motilin Receptors
- Muscarinic Receptor
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- Proteinase-Activated Receptors
- Purinergic Receptors
- Ryanodine receptor
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- Thrombin Receptor
- Vaniloid Receptor
- VIP and PACAP Receptors
- Neurotensin Receptors
- Urotensin Receptor
- Imidazoline receptor
- SMO Receptors
- Apelin Receptor
- β-arrestin/β2-adaptin
- KDM4
- Glucocorticoid Receptor
- Laminin Receptor
- AHR
- Amylin Receptor
- Bombesin Receptor
- Bradykinin Receptor
- CFTR
- CGRP Receptor
- CRFR
- Endothelin Receptor
- Ephrin Receptor
- Farnesoid X receptor (FXR)
- Glucagon Receptor
- Nuclear Receptor Ligands
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- Biomarkers and Buffer Solutions
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- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $47.25 | Total: $4,725.00 |
| 1 | 50 | $54.60 | Total: $2,730.00 |
| 1 | 25 | $64.05 | Total: $1,601.25 |
| 1 | 10 | $75.60 | Total: $756.00 |
| 1 | 5 | $89.25 | Total: $446.25 |
Data sheet
| Molecular Formula | C27H37F2N7O |
| Molecular Weight | 513.63 |
| CAS Numbers | 2756566-45-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNc1cc(ncn1)N1CCC2(CC1)CN(CC(=O)N2)c1cc(F)c(CN2CCC(C)(C)CC2)cc1F |
| References | Dolbois A, et al. 1,4,9-Triazaspiro[5.5]undecan-2-one Derivatives as Potent and Selective METTL3 Inhibitors. J Med Chem. 2021 Sep 9;64[17] 12738-12760. |
More info
UZH2 is a potent and selective METTL3 inhibitor with an IC50 value of 5 nM.