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View larger WR99210 hydrochloride(47326-86-3 free base)
AT17257L
CAS 30711-93-4
Molarity Calculation Cart®
HOW TO ORDER
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $54.00 | Total: $5,400.00 |
| 1 | 50 | $62.40 | Total: $3,120.00 |
| 1 | 25 | $73.20 | Total: $1,830.00 |
| 1 | 10 | $86.40 | Total: $864.00 |
| 1 | 5 | $102.00 | Total: $510.00 |
Data sheet
| Molecular Formula | C14H19Cl4N5O2 |
| Molecular Weight | 431.14 |
| CAS Numbers | 30711-93-4 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC1=NC(N)=NC(C)(C)N1OCCCOC2=CC(Cl)=C(Cl)C=C2Cl.[H]Cl |
| References | Canfield C J , Milhous W K , Ager A L , et al. PS-15 a potent, orally active antimalarial from a new class of folic acid antagonists.[J]. American Journal of Tropical Medicine & Hygiene, 1993, 49[1] 121. |
More info
WR99210 hydrochloride is a potent inhibitor of Plasmodium falciparum dihydrofolate reductase (pfDHFR), which is a major malarial drug target. It has subnanomolar potency for the wild type, double mutant and quadruple mutant dihydrofolate reductases.