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Rare Chemicals
- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $36.90 | Total: $3,690.00 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 5 | $69.70 | Total: $348.50 |
Data sheet
| Molecular Formula | C15H12ClN3O3S |
| Molecular Weight | 349.79 |
| CAS Numbers | 1449236-96-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | ClCC(=O)OC1=CC=CC(NC2=NS(=O)(=O)C3=C2C=CC=C3)=C1 |
| References | Magnaghi P, et al. Covalent and allosteric inhibitors of the ATPase VCPp97 induce cancer cell death. Nat Chem Biol. 2013 Sep;9[9] 548-56. |
More info
NMS-859 is an effective and covalent inhibitor of valosin-containing protein (VCP)p97 with IC50s of 0.37 ?M and 0.36 ?M for wild-type VCP in the presence of 60 ?M and 1 mM ATP in cells, respectively.