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View larger ACT-389949
AT10242
CAS 1258417-54-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $118.15 | Total: $590.75 |
| 1 | 10 | $100.08 | Total: $1,000.80 |
| 1 | 25 | $84.79 | Total: $2,119.75 |
| 1 | 50 | $72.28 | Total: $3,614.00 |
| 1 | 100 | $62.55 | Total: $6,255.00 |
Data sheet
| Molecular Formula | C20H18F2N6O3 |
| Molecular Weight | 428.39 |
| CAS Numbers | 1258417-54-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1nc(C(=O)Nc2cnn(Cc3nc(co3)C(C)(F)F)n2)c(o1)-c1cccc(C)c1 |
| References | Stalder AK,et al. Biomarker-guided clinical development of the first-in-class anti-inflammatory FPR2ALX agonist ACT-389949. Br J Clin Pharmacol. 2017 Mar;83[3] 476-486. |
More info
ACT-389949 is a potent and selective agonist of formyl peptide receptor type 2 (FPR2)Lipoxin A4 receptor (ALX), with an EC50 of 3 nM for FPR2ALX internalization into monocytes. It has the potential for the treatment of inflammatory disorders.