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Rare Chemicals
- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $19.80 | Total: $1,980.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 5 | $37.40 | Total: $187.00 |
Data sheet
| Molecular Formula | C23H20Cl2F3N5O2S |
| Molecular Weight | 558.4 |
| CAS Numbers | 2301866-59-9 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | FC(F)(F)Oc1ccc(Oc2ccnc(N3CCC(CC3)NC(=S)Nc3cccnc3)c2Cl)c(Cl)c1 |
| References | Ogasawara D, et al. Selective blockade of the lyso-PS lipase ABHD12 stimulates immune responses in vivo. Nat Chem Biol. 2018 Dec;14[12] 1099-1108. |
More info
DO-264 is an inhibitor of autohydrolase structural domain 12 (ABHD12) (IC50: 11 nM) and an inhibitor of cellular LysoPS degradation that enhances LPS-induced phagocytosis.