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DZ2002

AT11134

CAS 33231-14-0

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$96.00

$96.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $43.20 Total: $4,320.00
150 $49.92 Total: $2,496.00
125 $58.56 Total: $1,464.00
110 $69.12 Total: $691.20
15 $81.60 Total: $408.00

Data sheet

Molecular FormulaC10H13N5O3
Molecular Weight251.24
CAS Numbers33231-14-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC(=O)C(O)CCn1cnc2c(N)ncnc12
ReferencesWu QL, et al. Inhibition of S-adenosyl-L-homocysteine hydrolase induces immunosuppression. J Pharmacol Exp Ther. 2005 May;313[2] 705-11.

More info

DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity. It effectively prevents experimental dermal fibrosis by reversing the profibrotic phenotype in multiple cell types, making it useful for studying autoimmune diseases like lupus syndrome and systemic sclerosis.