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EG00229 View larger

EG00229

AT11153

CAS 1210945-69-9

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$38.00

$38.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.10 Total: $1,710.00
150 $19.76 Total: $988.00
125 $23.18 Total: $579.50
110 $27.36 Total: $273.60
15 $32.30 Total: $161.50

Data sheet

Molecular FormulaC19H20F3N7O7S3
Molecular Weight611.6
CAS Numbers1210945-69-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeOC(=O)C(F)(F)F.NC(=N)NCCC[C@H](NC(=O)c1sccc1NS(=O)(=O)c1cccc2nsnc12)C(O)=O
ReferencesJarvis A, et al. Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A [VEGF-A] interaction. J Med Chem. 2010 Mar 11;53[5] 2215-26.

More info

EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain with an IC50 value of 3 ?M. It does not affect the binding of VEGF-A to other receptors, such as VEGFR-1 and VEGFR-2.