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Rare Chemicals
- Protein Control Ligand
- Pathway Inhibitors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $19.80 | Total: $1,980.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 5 | $37.40 | Total: $187.00 |
Data sheet
| Molecular Formula | C22H24N4OS |
| Molecular Weight | 392.52 |
| CAS Numbers | 1587705-63-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1cc(cc(C)c1-c1csc(NC(=O)c2ccncc2)n1)N1CCCCC1 |
| References | Hu CM, et al. Novel small molecules disrupting Hec1Nek2 interaction ablate tumor progression by triggering Nek2 degradation through a death-trap mechanism. Oncogene. 2015 Mar 5;34[10] 1220-30. |
More info
INH154 is a highly potent inhibitor of Nek2 and Hec1 binding (INH), with IC50 values of 120 nM in MB468 cells and 200 nM in Hela cells.