Rare Chemicals

RH01386 View larger

RH01386

AT13867

CAS 301177-36-6

More details

Molarity Calculation Cart®

HOW TO ORDER

$90.00

$90.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $40.50 Total: $4,050.00
150 $46.80 Total: $2,340.00
125 $54.90 Total: $1,372.50
110 $64.80 Total: $648.00
15 $76.50 Total: $382.50

Data sheet

Molecular FormulaC18H15F3N4O3S
Molecular Weight424.4
CAS Numbers301177-36-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC(#N)C1=C(NC(SC2=C(N(=O)=O)C=C(C(F)(F)F)C=C2)=NC1=O)C3CCCCC3
ReferencesTran K, et al. Identification of small molecules that protect pancreatic ? cells against endoplasmic reticulum stress-induced cell death.ACS Chem Biol. 2014 Dec 19;9[12] 2796-806.

More info

RH01386 is a small molecule that prevents ER stress-induced ? cell dysfunction and death, inhibits proapoptotic gene expression, and restores ER stress-impaired glucose-stimulated insulin secretion responses, showing potential for type 2 diabetes treatment.