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View larger Aphidicolin
AT14304
CAS 38966-21-1
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $89.25 | Total: $446.25 |
| 1 | 10 | $75.60 | Total: $756.00 |
| 1 | 25 | $64.05 | Total: $1,601.25 |
| 1 | 50 | $54.60 | Total: $2,730.00 |
| 1 | 100 | $47.25 | Total: $4,725.00 |
Data sheet
| Molecular Formula | C20H34O4 |
| Molecular Weight | 338.48 |
| CAS Numbers | 38966-21-1 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [H][C@]12C[C@]3([H])C[C@]1(CC[C@]3(O)CO)[C@@]1(C)CC[C@@H](O)[C@@](C)(CO)[C@]1([H])CC2 |
| References | Dresler SL, et al. Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation. Biochemistry. 1988 Aug 23;27[17] 6379-83. |
More info
Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase ? and ?, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].