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Aphidicolin View larger

Aphidicolin

AT14304

CAS 38966-21-1

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$105.00

$105.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $47.25 Total: $4,725.00
150 $54.60 Total: $2,730.00
125 $64.05 Total: $1,601.25
110 $75.60 Total: $756.00
15 $89.25 Total: $446.25

Data sheet

Molecular FormulaC20H34O4
Molecular Weight338.48
CAS Numbers38966-21-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H][C@]12C[C@]3([H])C[C@]1(CC[C@]3(O)CO)[C@@]1(C)CC[C@@H](O)[C@@](C)(CO)[C@]1([H])CC2
ReferencesDresler SL, et al. Involvement of DNA polymerase delta in DNA repair synthesis in human fibroblasts at late times after ultraviolet irradiation. Biochemistry. 1988 Aug 23;27[17] 6379-83.

More info

Aphidicolin, an antibiotic derived from the mold Cephalosporium aphidicola, is a potent inhibitor of DNA (deoxyribonucleic acid) synthesis, effectively hindering the proliferation of herpes simplex virus[2]. It targets DNA polymerase ? and ?, disrupting mitotic cell division by affecting DNA polymerase activity[1]. Additionally, aphidicolin enhances apoptosis when combined with arabinosyl nucleosides in a human promyelocytic leukemia cell line[3].