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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $25.50 | Total: $127.50 |
| 1 | 10 | $21.60 | Total: $216.00 |
| 1 | 25 | $18.30 | Total: $457.50 |
| 1 | 50 | $15.60 | Total: $780.00 |
| 1 | 100 | $13.50 | Total: $1,350.00 |
Data sheet
| Molecular Formula | C22H30Cl4N2 |
| Molecular Weight | 464.3 |
| CAS Numbers | 366-93-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cl.Cl.Clc1ccccc1CNC[C@H]1CC[C@H](CNCc2ccccc2Cl)CC1 |
| References | Dvornik D, et al. Effect of long-term administration of AY-9944, an inhibitor of 7-dehydrocholesterol delta 7-reductase, on serum and tissue lipids in the rat. J Lipid Res. 1968 Sep;9[5] 587-95. |
More info
AY 9944 is a specific cholesterol biosynthesis inhibitor that targets the 7-dehydrocholesterol ?7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 also inhibits sterol ?7-?8 isomerase in cultured embryos, leading to the accumulation of cholest-8-en-3?-ol[1][2][3]. Additionally, AY 9944 causes hypocholesterolemia and accumulation of 7DHC.