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SBI-425

AT16859

CAS 1451272-71-1

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC13H12ClN3O4S
Molecular Weight341.77
CAS Numbers1451272-71-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOc1ccc(Cl)cc1S(=O)(=O)Nc1cncc(c1)C(N)=O
ReferencesPinkerton AB, et al. Discovery of 5-[[5-chloro-2-methoxyphenyl]sulfonamido]nicotinamide [SBI-425], a potent and orally bioavailable tissue-nonspecific alkaline phosphatase [TNAP] inhibitor. Bioorg Med Chem Lett. 2018 Jan 1;28[1] 31-34.

More info

SBI-425 is an effective and orally bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP). SBI-425 effectively inhibits TNAP in the vasculature and improves cardiovascular parameters and survival without a detectable change in the bone.