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KRM-III

AT35885

CAS 79220-94-3

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$41.00

$41.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $18.45 Total: $1,845.00
150 $21.32 Total: $1,066.00
125 $25.01 Total: $625.25
110 $29.52 Total: $295.20
15 $34.85 Total: $174.25

Data sheet

Molecular FormulaC15H12N2S
Molecular Weight252.33
CAS Numbers79220-94-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeS=c1[nH]c(cn1-c1ccccc1)-c1ccccc1
ReferencesJung EJ, et al. Oral administration of 1,4-aryl-2-mercaptoimidazole inhibits T-cell proliferation and reduces clinical severity in the murine experimental autoimmune encephalomyelitis model. J Pharmacol Exp Ther. 2009 Dec;331[3] 1005-13.

More info

KRM-III is an orally active T cell antigen receptor (TCR) inhibitor with anti-inflammatory activity that potently inhibits TCR and myristate acetatefosfomycinionomycin-induced NFAT nuclear factor activation and T cell proliferation, with an IC50 of approximately 5 ?M.