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Acid Ceramidase-IN-1 View larger

Acid Ceramidase-IN-1

AT40051

CAS 2415225-30-6

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$91.00

$91.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $40.95 Total: $4,095.00
150 $47.32 Total: $2,366.00
125 $55.51 Total: $1,387.75
110 $65.52 Total: $655.20
15 $77.35 Total: $386.75

Data sheet

Molecular FormulaC18H25N3O3
Molecular Weight331.41
CAS Numbers2415225-30-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC(C)CNC(=O)n1c2ccc(cc2oc1=O)C1CCN(C)CC1
ReferencesDi Martino S, et al. Lead Optimization of Benzoxazolone Carboxamides as Orally Bioavailable and CNS Penetrant Acid Ceramidase Inhibitors. J Med Chem. 2020;63[7] 3634-3664.

More info

Acid Ceramidase-IN-1 is a highly effective, orally bioavailable inhibitor of acid ceramidase (AC, ASAH-1) with an IC50 of 0.166 ?M and exhibits exceptional brain penetration capabilities in mice.