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Rare Chemicals
- Protein Control Ligand
- Pathway Inhibitors
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- Kinase Inhibitors
- Protease
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- p18
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $15.75 | Total: $1,575.00 |
| 1 | 50 | $18.20 | Total: $910.00 |
| 1 | 25 | $21.35 | Total: $533.75 |
| 1 | 10 | $25.20 | Total: $252.00 |
| 1 | 5 | $29.75 | Total: $148.75 |
Data sheet
| Molecular Formula | C21H22N2O6S |
| Molecular Weight | 430.47 |
| CAS Numbers | 1401089-31-3 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCOC(=O)CNC(=O)C(N(C(=O)C#C)c1ccc(OC)cc1OC)c1cccs1 |
| References | Xu S, et al. Discovery of an orally active small-molecule irreversible inhibitor of protein disulfide isomerase for ovarian cancer treatment. Proc Natl Acad Sci U S A. 2012;109[40] 16348-16353. |
More info
PACMA 31 is an irreversible and covalent inhibitor of protein disulfide isomerase (PDI) with an IC50 of 10 ?M. PACMA 31 significantly suppresses ovarian tumor growth and exhibits tumor targeting ability.