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View larger SPI--112Me
AT4627
CAS 1243685-62-2
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $29.75 | Total: $148.75 |
| 1 | 10 | $25.20 | Total: $252.00 |
| 1 | 25 | $21.35 | Total: $533.75 |
| 1 | 50 | $18.20 | Total: $910.00 |
| 1 | 100 | $15.75 | Total: $1,575.00 |
Data sheet
| Molecular Formula | C23H19FN4O5S |
| Molecular Weight | 482.48 |
| CAS Numbers | 1243685-62-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(NC1=CC(C(OC)=O)=CC=C1)=C2C=3C(NC2=O)=CC=C(S(NCC4=CC=C(F)C=C4)(=O)=O)C3 |
| References | Win-Piazza, H., Schneeberger, V., Chen, L., Pernazza, D., Lawrence, H., & Sebti, S. et al. [2012]. Enhanced anti-melanoma efficacy of interferon alfa-2b via inhibition of Shp2. |
More info
SPI--112Me, a prodrug of SPI-112, preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by more than 20-fold in cell-free assays.