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SPI--112Me View larger

SPI--112Me

AT4627

CAS 1243685-62-2

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$35.00

$35.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $15.75 Total: $1,575.00
150 $18.20 Total: $910.00
125 $21.35 Total: $533.75
110 $25.20 Total: $252.00
15 $29.75 Total: $148.75

Data sheet

Molecular FormulaC23H19FN4O5S
Molecular Weight482.48
CAS Numbers1243685-62-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(NC1=CC(C(OC)=O)=CC=C1)=C2C=3C(NC2=O)=CC=C(S(NCC4=CC=C(F)C=C4)(=O)=O)C3
ReferencesWin-Piazza, H., Schneeberger, V., Chen, L., Pernazza, D., Lawrence, H., & Sebti, S. et al. [2012]. Enhanced anti-melanoma efficacy of interferon alfa-2b via inhibition of Shp2.

More info

SPI--112Me, a prodrug of SPI-112, preferentially inhibits the PTPase activity of Shp2 over Shp1 and PTP1B by more than 20-fold in cell-free assays.