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Rare Chemicals
- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $37.35 | Total: $3,735.00 |
| 1 | 50 | $43.16 | Total: $2,158.00 |
| 1 | 25 | $50.63 | Total: $1,265.75 |
| 1 | 10 | $59.76 | Total: $597.60 |
| 1 | 5 | $70.55 | Total: $352.75 |
Data sheet
| Molecular Formula | C20H20ClFN4O5S |
| Molecular Weight | 482.91 |
| CAS Numbers | 2166023-31-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)cc1C(N)=O)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C |
| References | Ueno H, et, al. TAS1553, a small molecule subunit interaction inhibitor of ribonucleotide reductase, exhibits antitumor activity by causing DNA replication stress. Commun Biol. 2022 Jun 9;5[1] 571. |
More info
TAS1553 is a highly effective, orally bioavailable protein-protein interaction (PPI) inhibitor with an IC50 value of 0.0396 ?M. It effectively hinders DNA replication and diminishes the intracellular dATP pool. Moreover, TAS1553 induces apoptosis, making it a valuable compound in cancer research [1].