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View larger mTOR inhibitor 9a
AT67705
CAS 1144075-32-0
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $253.30 | Total: $1,266.50 |
| 1 | 10 | $214.56 | Total: $2,145.60 |
| 1 | 25 | $181.78 | Total: $4,544.50 |
| 1 | 50 | $154.96 | Total: $7,748.00 |
| 1 | 100 | $134.10 | Total: $13,410.00 |
Data sheet
| Molecular Formula | C20H21N5O2S |
| Molecular Weight | 395.48 |
| CAS Numbers | 1144075-32-0 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(NC)=O)C1=CC=C(C2=NC(=C3C(=N2)C=CS3)N4CC5OC(C4)CC5)C=C1 |
| References | Verheijen JC, et al. Discovery of 2-arylthieno[3,2-d]pyrimidines containing 8-oxa-3-azabi-cyclo[3.2.1]octane in the 4-position as potent inhibitors of mTOR with selectivity over PI3K. Bioorg Med Chem Lett. 2010;20[1] 375-379. |
More info
mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.