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Rare Chemicals
- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $44.55 | Total: $4,455.00 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 5 | $84.15 | Total: $420.75 |
Data sheet
| Molecular Formula | C23H21NO3 |
| Molecular Weight | 359.42 |
| CAS Numbers | 2642218-43-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(C)C1(CC)C=2C(C=3C(C(=O)C2OCC4=CC=CC=C4)=CC=CC3)=NC1=O |
| References | David C Rawling, et al. Small-Molecule Antagonists of the RIG-I Innate Immune Receptor. ACS Chem Biol. 2020 Feb 21;15[2] 311-317. |
More info
RIG012 is a potent RIG-I inhibitor with an IC50 of 0.71 ?M (measured by NADH-coupled ATPase), and it inhibits the expression of IFN-? and ISG hRsad2.