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CLK8 View larger

CLK8

AT73573

CAS 898920-65-5

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$49.00

$49.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $22.05 Total: $2,205.00
150 $25.48 Total: $1,274.00
125 $29.89 Total: $747.25
110 $35.28 Total: $352.80
15 $41.65 Total: $208.25

Data sheet

Molecular FormulaC29H26N2O6
Molecular Weight498.53
CAS Numbers898920-65-5
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1OC2=C(C(OCC(=O)NC=3C=CC=CC3C(=O)N)=CC=4OC(C)(C)CCC42)C(=C1)C=5C=CC=CC5
ReferencesDoruk YU, et al. A CLOCK-binding small molecule disrupts the interaction between CLOCK and BMAL1 and enhances circadian rhythm amplitude. J Biol Chem. 2020 Mar 13;295[11] 3518-3531.

More info

CLK8 is a selective CLOCK inhibitor that binds to and interferes with CLOCK activity, disrupts the interaction between CLOCK and BMAL1, and modulates circadian rhythm amplitude.CLK8 can be used to study circadian rhythm-related disorders.