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PDS-0330 View larger

PDS-0330

AT73593

CAS 2904682-19-3

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$71.00

$71.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.95 Total: $3,195.00
150 $36.92 Total: $1,846.00
125 $43.31 Total: $1,082.75
110 $51.12 Total: $511.20
15 $60.35 Total: $301.75

Data sheet

Molecular FormulaC25H17N3O2S
Molecular Weight423.49
CAS Numbers2904682-19-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN(C(NC(=O)C1=CC2=C(C=C1)C=CC=C2)=S)C3=CC=C(C4=NC=5C(O4)=CC=CC5)C=C3
ReferencesFatima I, et al. Identification and characterization of a first-generation inhibitor of claudin-1 in colon cancer progression and metastasis. Biomed Pharmacother. 2023;159 114255.

More info

PDS-0330 is a claudin-1 small molecule inhibitor inhibitor.PDS-0330 inhibits claudin-1-dependent CRC progression and binds directly and specifically to claudin-1 with micromolar affinity.PDS-0330 exhibits well characterized pharmacokinetic properties with antitumor and Chemosensitizing activity.PDS-0330 interferes with claudin-1 Src association to inhibit CRC progression and metastasis.