Rare Chemicals

FXR agonist 3 View larger

FXR agonist 3

AT74996

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$102.00

$102.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $45.90 Total: $4,590.00
150 $53.04 Total: $2,652.00
125 $62.22 Total: $1,555.50
110 $73.44 Total: $734.40
15 $86.70 Total: $433.50

Data sheet

Molecular FormulaC28H28BrNO4
Molecular Weight521.12
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCOC1=CC2=C(C=C1OC)CC[N+]3=C2C=C4C(C(OCC5=CC=CC(C)=C5)=C(OC)C=C4)=C3.[Br-]

More info

FXR agonist 3 is an anti-NASH compound with antifibrotic and anti-fibrotic activity, inhibiting the expression of COL1A1, TGF-?1, ?-SMA, and TIMP1, with an IC50 value of 8.19 ?molL for COL1A1. FXR agonist 3 ameliorates CDAHFD and BDL-induced liver injury in vivo by activating FXR.