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Rare Chemicals
- Protein Control Ligand
- Pathway Inhibitors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $25.20 | Total: $2,520.00 |
| 1 | 50 | $29.12 | Total: $1,456.00 |
| 1 | 25 | $34.16 | Total: $854.00 |
| 1 | 10 | $40.32 | Total: $403.20 |
| 1 | 5 | $47.60 | Total: $238.00 |
Data sheet
| Molecular Formula | C19H20BrF2N3O |
| Molecular Weight | 424.28 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(NCC1=CC=C(Br)C=C1)N(CC2)CCN2CC3=CC(F)=CC(F)=C3 |
| References | Zhou LL, et al. Selective activator of human ClpP triggers cell cycle arrest to inhibit lung squamous cell carcinoma. Nat Commun. 2023 Nov 3;14[1] 7069. |
More info
ZK53 is a selective and potent activator of mitochondrial casein hydrolase protease P (HsClpP).ZK53 induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.ZK53 inhibits tumour growth in xenografts and native mouse models.