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IGS-1.76 View larger

IGS-1.76

AT8784

CAS 313480-47-6

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$71.00

$71.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $31.95 Total: $3,195.00
150 $36.92 Total: $1,846.00
125 $43.31 Total: $1,082.75
110 $51.12 Total: $511.20
15 $60.35 Total: $301.75

Data sheet

Molecular FormulaC22H18N2OS
Molecular Weight358.46
CAS Numbers313480-47-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(CC(c1ccccc1)c1ccccc1)Nc1nc2ccccc2s1
ReferencesCarlos Roca, et al. Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators. J Med Chem. 2018 Jul 26;61[14] 5910-5921.

More info

IGS-1.76 exhibits pronounced affinity towards hNCS-1 and effectively modulates the interaction between hNCS-1 and Ric8a. Moreover, IGS-1.76 proficiently inhibits the complex formed by human NCS-1 and Ric8a.