Rare Chemicals

FB23 View larger

FB23

AT8874

CAS 2243736-35-6

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$38.00

$38.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.10 Total: $1,710.00
150 $19.76 Total: $988.00
125 $23.18 Total: $579.50
110 $27.36 Total: $273.60
15 $32.30 Total: $161.50

Data sheet

Molecular FormulaC18H14Cl2N2O3
Molecular Weight377.22
CAS Numbers2243736-35-6
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1noc(C)c1-c1cc(Cl)c(Nc2ccccc2C(O)=O)c(Cl)c1
ReferencesSmall-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia[J]. Science Foundation in China, 2019.

More info

FB23 directly binds to FTO and selectively inhibits FTO's m6A demethylase activity. (FTO, an mRNA N6-methyladenosine (m6A) demethylase, was reported to promote leukemogenesis.)