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Rare Chemicals
- Protein Control Ligand
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View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $36.90 | Total: $3,690.00 |
| 1 | 50 | $42.64 | Total: $2,132.00 |
| 1 | 25 | $50.02 | Total: $1,250.50 |
| 1 | 10 | $59.04 | Total: $590.40 |
| 1 | 5 | $69.70 | Total: $348.50 |
Data sheet
| Molecular Formula | C18H17F3N6O2 |
| Molecular Weight | 406.36 |
| CAS Numbers | 1458630-17-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCNC1=NN2C(C=C1)=NC=C2C3=CC4=C(NN=C4)C=C3.O=C(O)C(F)(F)F |
| References | Huertas D, et al. Antitumor activity of a small-molecule inhibitor of the histone kinase Haspin. Oncogene. 2012 Mar 15;31[11] 1408-18. |
More info
CHR-6494 TFA is a potent haspin inhibitor with an IC50 of 2 nM, inhibiting histone H3T3 phosphorylation. It induces apoptosis in cancer cells, including melanoma and breast cancer, and is useful for cancer research.