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Rare Chemicals
- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $59.85 | Total: $5,985.00 |
| 1 | 50 | $69.16 | Total: $3,458.00 |
| 1 | 25 | $81.13 | Total: $2,028.25 |
| 1 | 10 | $95.76 | Total: $957.60 |
| 1 | 5 | $113.05 | Total: $565.25 |
Data sheet
| Molecular Formula | C23H24N2O3 |
| Molecular Weight | 376.45 |
| CAS Numbers | 2234271-86-2 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=CC(NCCC1=C(OCC=C)C=CC=C1)=O)C=2C=3C(=C(OC)C=CC3)NC2 |
| References | Perron A, et al. Small-molecule screening yields a compound that inhibits the cancer-associated transcription factor Hes1 via the PHB2 chaperone. J Biol Chem. 2018 May 25;293[21] 8285-8294. |
More info
JI130 is able to impair the ability of Hes1 to repress transcription. JI130 treatment significantly reduced tumor volume in a murine pancreatic tumor xenograft model.