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G280-9 acetate(156761-76-1 free base) View larger

G280-9 acetate(156761-76-1 free base)

ATP1543L

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HOW TO ORDER

$37.00

$37.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $16.65 Total: $1,665.00
150 $19.24 Total: $962.00
125 $22.57 Total: $564.25
110 $26.64 Total: $266.40
15 $31.45 Total: $157.25

Data sheet

Molecular FormulaC46H71N9O16
Molecular Weight1006.12
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C([C@@H](NC([C@@H](NC([C@H](CC1=CC=C(C=C1)O)N)=O)CC(C)C)=O)CCC(O)=O)N2CCC[C@H]2C(NCC(N3CCC[C@H]3C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@@H](C)O)=O)C(C)C)=O)=O)=O.CC(O)=O
ReferencesPass HA, et al. Immunization of patients with melanoma peptide vaccines immunologic assessment using the ELISPOT assay. Cancer J Sci Am. 1998 Sep-Oct;4[5] 316-23.

More info

G280-9 acetate is a common melanoma gp100 epitope restricted by MHC-associated HLA-A2. The G280-9 sequence is unique because it could be recognized by cytotoxic T lymphocytes at very low concentrations, however it shows low total immunogenicity that may be attributable to relatively low affinity of this peptide for the HLA-A2.