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> Rare Chemicals>Pep 2-8 ammonium salt(1541011-97-5 free base)

Rare Chemicals

Pep 2-8 ammonium salt(1541011-97-5 free base) View larger

Pep 2-8 ammonium salt(1541011-97-5 free base)

ATP1881L1

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$116.00

$116.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $98.60 Total: $493.00
110 $83.52 Total: $835.20
125 $70.76 Total: $1,769.00
150 $60.32 Total: $3,016.00
1100 $52.20 Total: $5,220.00

Data sheet

Molecular FormulaC83H113N17O24
Molecular Weight1732.91
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC[C@@H](O)[C@H](NC(C)=O)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)C(C)C)=O)CC1=CNC2=CC=CC=C21)=O)CC(O)=O)=O)CC(C)C)=O)CC3=CC=C(O)C=C3)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC4=CNC5=CC=CC=C54)=O)CO)=O)[C@H](O)C)=O)CC6=CC=CC=C6)=O)C(C)C)=O.N
ReferencesZhang et al [2014] Identification of a small peptide that inhibits PCSK9 protein binding to the low density lipoprotein receptor. J.Biol.Chem. 289 942 PMID

More info

Pep 2-8 ammonium salt is Proprotein convertase subtilisinkexin type 9 (PCSK9) inhibitor. Potent inhibitor of PCSK9 binding to LDL receptor (IC50 = 0.8 ?M). Restores LDL uptake in HepG2 cells treated with PCSK9.