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Cuprizone

AT65013

CAS 370-81-0

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Data sheet

Molecular FormulaC14H22N4O2
Molecular Weight278.35
CAS Numbers370-81-0
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(NN=C1CCCCC1)C(=O)NN=C1CCCCC1
ReferencesSuzuki K, et al. Status spongiosus of CNS and hepatic changes induced by cuprizone [biscyclohexanone oxalyldihydrazone]. Am J Pathol. 1969 Feb;54[2] 307-25.

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Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response.