RAS

ML-210 View larger

ML-210

AT8375

CAS 1360705-96-9

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$29.00

$29.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.05 Total: $1,305.00
150 $15.08 Total: $754.00
125 $17.69 Total: $442.25
110 $20.88 Total: $208.80
15 $24.65 Total: $123.25

Data sheet

Molecular FormulaC22H20Cl2N4O4
Molecular Weight475.32
CAS Numbers1360705-96-9
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1onc(C(=O)N2CCN(CC2)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)c1[N+]([O-])=O
ReferencesBittker JA, Weiwer M, Lewis T,et al. Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 2[J]. 2010.

More info

ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor (EC50=30 nM) that is covalent and selective. ML-210 has antitumor activity and induces ferroptosis.