Reductase

WJ-39 View larger

WJ-39

AT84345

CAS 3009908-95-3

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$99.00

$99.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $44.55 Total: $4,455.00
150 $51.48 Total: $2,574.00
125 $60.39 Total: $1,509.75
110 $71.28 Total: $712.80
15 $84.15 Total: $420.75

Data sheet

Molecular FormulaC19H14Cl2KNO4
Molecular Weight430.32
CAS Numbers3009908-95-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C(CN1C=C(CC2=C(Cl)C(Cl)=CC=C2)C(C3=CC(OC)=CC=C31)=O)[O-].[K+]
ReferencesYang L, et al. An aldose reductase inhibitor, WJ-39, ameliorates renal tubular injury in diabetic nephropathy by activating PINK1Parkin signaling. Eur J Pharmacol. 2024 Mar 15;967 176376.

More info

WJ-39 is an orally active aldose reductase (AR) inhibitor that ameliorates renal lesions in diabetic nephropathy through activation of Nrf2 signaling, and may be used to ameliorate renal insufficiency and fibrosis.WJ-39 inhibits oxidative stress and inhibits the activation of the inflammatory vesicle of the oligomerization structural domain-like receptor family, pyrin structural domain 3 (NLRP3).