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View larger S18-000003
AT16832
CAS 2068119-11-7
1000 Items
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Data sheet
| Molecular Formula | C26H25F3N2O4S |
| Molecular Weight | 518.55 |
| CAS Numbers | 2068119-11-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(c(F)c2)C(C)(C)C(=O)Nc2ccc(F)cc2F)cc1 |
| References | Sasaki Y, et al. Discovery of a potent orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t [ROR?t] inhibitor, S18-000003. Bioorg Med Chem Lett. 2018 Dec 1;28[22] 3549-3553. |
More info
S18-000003 is an effective orally bioavailable retinoic acid receptor-related orphan receptor-gamma-t inhibitor (IC50: 29 nM). S18-000003 inhibits IL-17 production.