ROR

GSK805 View larger

GSK805

AT7388

CAS 1426802-50-7

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$43.00

$43.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $19.35 Total: $1,935.00
150 $22.36 Total: $1,118.00
125 $26.23 Total: $655.75
110 $30.96 Total: $309.60
15 $36.55 Total: $182.75

Data sheet

Molecular FormulaC23H18Cl2F3NO4S
Molecular Weight532.36
CAS Numbers1426802-50-7
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(c(Cl)c2)-c2ccccc2OC(F)(F)F)cc1
ReferencesXiao S , Yosef N , Yang J , et al. Small-Molecule ROR?t Antagonists Inhibit T Helper 17 Cell Transcriptional Network by Divergent Mechanisms[J]. Immunity, 2014, 40[4] 477-489.

More info

GSK805 is a potent, orally bioavailable retinoid-related orphan receptor gamma t (ROR?t) inverse agonist that interacts with the receptor's putative ligand binding domain without exerting significant effects on DNA binding