SARS-CoV

SARS-CoV-2 Mpro-IN-9 View larger

SARS-CoV-2 Mpro-IN-9

AT79455

CAS 2754370-99-3

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$249.00

$249.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $112.05 Total: $11,205.00
150 $129.48 Total: $6,474.00
125 $151.89 Total: $3,797.25
110 $179.28 Total: $1,792.80
15 $211.65 Total: $1,058.25

Data sheet

Molecular FormulaC20H14N2O4
Molecular Weight346.34
CAS Numbers2754370-99-3
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeO=C1C=2C(N=C(C=3C=CC=CC3)N1C=4C=CC=CC4)=CC(O)=C(O)C2O
ReferencesSullivan SM, et al. Vaxfectin a versatile adjuvant for plasmid DNA- and protein-based vaccines. Expert Opin Drug Deliv. 2010 Dec;7[12] 1433-46.

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SARS-CoV-2 Mpro-IN-9 (compound c7), a nonpeptidic, noncovalent inhibitor of SARS-CoV-2 main protease (Mpro), exhibits potent inhibitory action (IC50 = 0.085 ?M) and improved physicochemical and drug metabolism and pharmacokinetics (DMPK) properties. It effectively suppresses viral replication in SARS-CoV-2-infected Vero E6 cells (EC50 = 1.10 ?M) and demonstrates low cytotoxicity (CC50 > 50 ?M) [1].