Sigma Receptors

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Blarcamesine (AE-37 HCl)

AOB6585

CAS No: 195615-84-0

 

Chemical Name: AE-37, Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride

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$17.00

$17.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $7.65 Total: $765.00
150 $8.84 Total: $442.00
125 $10.37 Total: $259.25
110 $12.24 Total: $122.40
15 $14.45 Total: $72.25

Data sheet

Molecular FormulaC19H24ClNO
Molecular Weight317.86
CAS Numbers195615-84-0
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymAE-37 hydrochloride
IUPAC/Chemical Name1-(2,2-diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride
InChl KeyFEQOLYDPQKHFTD-UHFFFAOYSA-N
InChl CodeInChI=1S/C19H23NO.ClH/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17;/h3-12,18H,13-15H2,1-2H3;1H
SMILES CodeCN(C)CC1C(C2=CC=CC=C2)(C3=CC=CC=C3)OCC1.[H]Cl
References1) Goguadze N, Zhuravliova E, Morin D, Mikeladze D, Maurice T. Sigma-1 Receptor Agonists Induce Oxidative Stress in Mitochondria and Enhance Complex I Activity in Physiological Condition but Protect Against Pathological Oxidative Stress. Neurotox Res. 2017 Nov 10.

2) Maurice T. Protection by sigma-1 receptor agonists is synergic with donepezil, but not with memantine, in a mouse model of amyloid-induced memory impairments. Behav Brain Res. 2016 Jan 1;296:270-278.

3) Villard V, Espallergues J, Keller E, Vamvakides A, Maurice T. Anti-amnesic and neuroprotective potentials of the mixed muscarinic receptor/sigma 1 (σ1) ligand, a novel aminotetrahydrofuran derivative. J Psychopharmacol. 2011 Aug;25(8):1101-17.

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Neuroprotective agent and σ1 agonist