Sirtuin

SRT 1720 dihydrochloride[925434-55-5(free base)] View larger

SRT 1720 dihydrochloride[925434-55-5(free base)]

AT5124

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$48.00

$48.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $21.60 Total: $2,160.00
150 $24.96 Total: $1,248.00
125 $29.28 Total: $732.00
110 $34.56 Total: $345.60
15 $40.80 Total: $204.00

Data sheet

Molecular FormulaC25H25Cl2N7OS
Molecular Weight542.48
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCl.Cl.O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cnc2ccccc2n1
ReferencesMilne JC et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 2007 Nov 29;450[7170] 712-6

More info

SRT 1720 is a selective activator of SIRT1 (EC1.5: 0.16 ?M) and shows less potent activities on SIRT2 (EC1.5: 37 ?M) and SIRT3 (EC1.5: 300 ?M).