Sodium Channels

PF-06869206 View larger

PF-06869206

AOB31600

CAS: 2227425-05-8

 

Chemical Name: (S)-3-Chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile

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$17.50

$17.50 per mg

Quantity Discount Table - Order More To Get More Price Discount

Quantity (mg or Unit)Unit Price ($/mg or $/Unit)Final Price
100 $7.88 Total: $787.50
50 $9.10 Total: $455.00
25 $10.68 Total: $266.88
10 $12.60 Total: $126.00
5 $14.88 Total: $74.38

Data sheet

Molecular FormulaC15H14ClF3N4O2
Molecular Weight374.75
CAS Numbers2227425-05-8
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymPF-06869206; PF 06869206; PF06869206
IUPAC/Chemical NameS)-3-chloro-7-(2-(hydroxymethyl)morpholino)-2-methyl-5-(trifluoromethyl)-1H-pyrrolo[3,2-b]pyridine-6-carbonitrile
InChl KeyATFQBBCQZKVZJN-QMMMGPOBSA-N
InChl CodeInChI=1S/C15H14ClF3N4O2/c1-7-10(16)11-12(21-7)13(23-2-3-25-8(5-23)6-24)9(4-20)14(22-11)15(17,18)19/h8,21,24H,2-3,5-6H2,1H3/t8-/m0/s1
SMILES CodeN#CC1=C(C(F)(F)F)N=C2C(NC(C)=C2Cl)=C1N3C[C@@H](CO)OCC3
ReferencesFilipski KJ, et al. Discovery of Orally Bioavailable Selective Inhibitors of the Sodium-Phosphate Cotransporter NaPi2a (SLC34A1). ACS Med Chem Lett. 2018 Apr 12;9(5):440-445.

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Novel selective inhibitor of sodium-phosphate cotransporter 2a (NaPi2a or SLC34A1)