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PF-05089771 Tosylate
AOB9577
CAS No: 1430806-04-4
Chemical Name: 4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-benzenesulfonamide Tosylate
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $8.55 | Total: $855.00 |
| 1 | 50 | $9.88 | Total: $494.00 |
| 1 | 25 | $11.59 | Total: $289.75 |
| 1 | 10 | $13.68 | Total: $136.80 |
| 1 | 5 | $16.15 | Total: $80.75 |
Data sheet
| Molecular Formula | C25H20Cl2FN5O6S3 |
| Molecular Weight | 672.56 |
| CAS Numbers | 1430806-04-4 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| IUPAC/Chemical Name | 4-[2-(3-amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolyl-4-benzenesulfonamide, monomethylbenzenesulfonate |
| InChl Key | NVKBPDYKPNYMDR-UHFFFAOYSA-N |
| InChl Code | InChI=1S/C18H12Cl2FN5O3S2.C7H8O3S/c19-9-1-2-14(10(3-9)11-6-24-25-18(11)22)29-15-5-13(21)16(4-12(15)20)31(27,28)26-17-7-30-8-23-17;1-6-2-4-7(5-3-6)11(8,9)10/h1-8,26H,(H3,22,24,25);2-5H,1H3,(H,8,9,10) |
| SMILES Code | ClC1=C(OC2=CC=C(Cl)C=C2C3=CNN=C3N)C=C(F)C(S(NC4=CSC=N4)(=O)=O)=C1.CC5=CC=C(S(O)(=O)=O)C=C5 |
| References | Alexandrou, A.J., Brown, A.R., Chapman, M.L., et al. Subtype-selective small molecule inhibitors reveal a fundamental role for Nav1.7 in nociceptor electrogenesis, axonal conduction and presynaptic release. PLoS One 11(4), e0152405 (2016). |
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Novel potent and selective human Nav1.7 blocker