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AOB2459
CAS No: 1137359-47-7
Chemical Name: Methyl [2,3-O-bis(Benzo[1,3]dioxol-5-yl-carbamoyl)]-4-O-(4-ethoxycarbonyl-phenylcarbamoyl)-alpha-D-glucopyranoside
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Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
---|---|---|---|
1 | 100 | $6.75 | Total: $675.00 |
1 | 50 | $7.80 | Total: $390.00 |
1 | 25 | $9.15 | Total: $228.75 |
1 | 10 | $10.80 | Total: $108.00 |
1 | 5 | $12.75 | Total: $63.75 |
Molecular Formula | C33H33N3O15 |
Molecular Weight | 711.63 |
CAS Numbers | 1137359-47-7 |
Storage Condition | 0°C (short term), -20°C (long term), desiccated |
Solubility | 100 mM in DMSO |
Purity | 98% by HPLC |
Novel Inducer of PDX1 Gene and Protein Expression, Changing the Epigenetic Status of the PDX1 Promoter. Up regulates PDX1 expression in both primary human islets and ductal cells. Induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. Increases insulin expression in PANC-1 cells, primary human islets and human duct-derived cells.
Yuan et al (2013) A small-molecule inducer of PDX1 expression identified by high-throughput screening. Chem.Biol. 20 1513. PMID: 24290880.