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View larger Bozitinib
AT10585
CAS 1440964-89-5
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $78.20 | Total: $391.00 |
| 1 | 10 | $66.24 | Total: $662.40 |
| 1 | 25 | $56.12 | Total: $1,403.00 |
| 1 | 50 | $47.84 | Total: $2,392.00 |
| 1 | 100 | $41.40 | Total: $4,140.00 |
Data sheet
| Molecular Formula | C20H15F3N8 |
| Molecular Weight | 424.38 |
| CAS Numbers | 1440964-89-5 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cn1cc2cc(c(F)cc2n1)C(F)(F)c1nnc2ccc(nn12)-c1cnn(c1)C1CC1 |
| References | Hu H, et al. Mutational Landscape of Secondary Glioblastoma Guides MET-Targeted Trial in Brain Tumor. Cell. 2018 Nov 29;175[6] 1665-1678.e18. |
More info
Bozitinib (PLB-1001) (PLB-1001) is a highly selective inhibitor of the c-MET kinase with blood-brain barrier permeability. Bozitinib binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily.