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Stem Cell Research
- Protein Control Ligand
- Pathway Inhibitors
- Enzyme Inhibitors
- Kinase Inhibitors
- Protease
- Synthase
- p18
- p38
- p53
- p70
- p90
- Peptidase
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- Ceramide Turnover Enzymes
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- Glycerophospholipid Turnover Enzymes
- Hydroxylases
- Ubiquitin-Activating Enzyme
- Adenosine Deaminase
- Clathrin
- Nuclease
- p68
- ACE
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- Transporter Inhibitors
- Cell Inhibition
- Synthase
- Receptor Tyrosine Phosphatases (RTP)
- AChE
- Peptidase
- Autophagy
- Toll-Like Receptor (TLR)
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- Function Modulators
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- G Protein-Coupled Receptor Ligands
- 5HT Receptors
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- CCK Receptors
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- EAA Receptors
- Ghrelin Receptors
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- Motilin Receptors
- Muscarinic Receptor
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- Orphan Receptors
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- Purinergic Receptors
- Ryanodine receptor
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- Urotensin Receptor
- Imidazoline receptor
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- β-arrestin/β2-adaptin
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- Ephrin Receptor
- Farnesoid X receptor (FXR)
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- Nuclear Receptor Ligands
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- Transcription Factors
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- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
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- Metabolites
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- Customized Screening Library
- Ultra Pure Pharmacological Standard
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- Proteins and Antibodies
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- Molecular Glues
- PROTAC Linker
- SARS-CoV
View larger Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Data sheet
| Molecular Formula | C31H26F2N4O6 |
| Molecular Weight | 588.56 |
| CAS Numbers | 1437321-24-8 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)cc5)c4=O)cc3F)c2cc1OC |
| References | Miknyoczki S, Cheng M, Hudkins R, et al. Abstract C275 CEP-40783 A potent and selective AXLc-Met inhibitor for use in breast, non-small cell lung [NSCLC], and pancreatic cancers.[J]. Molecular Cancer Therapeutics, 2013, 12[11_Supplement] C275-C275. |
More info
CEP-40783 (RXDX-106) is an effective, specific and orally active AXLc-Met inhibitor (IC50: 712 nM). It also inhibits MER and TYRO3 (IC50: 2919 nM).