Array
(
)
1
> Nuclear Receptor Ligands>Steroid Hormone Receptors>Hexarelin Acetate

Steroid Hormone Receptors

Hexarelin Acetate View larger

Hexarelin Acetate

AOB36105

CAS: 208251-52-9 (free base: 140703-51-1)

 

Chemical Name: HEX; Examorelin; EP-23905; MF-6003; His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2

More details

999 Items

Molarity Calculation Cart®

HOW TO ORDER

$39.00

$39.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $33.15 Total: $165.75
110 $28.08 Total: $280.80
125 $23.79 Total: $594.75
150 $20.28 Total: $1,014.00
1100 $17.55 Total: $1,755.00

Data sheet

Molecular FormulaC24H21ClFN5O3
Molecular Weight481.91
CAS Numbers1637542-33-6
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
IUPAC/Chemical NameHEX; Examorelin; EP-23905; MF-6003; His-D-2-methyl-Trp-Ala-Trp-D-Phe-Lys-NH2
InChl KeyRVWNMGKSNGWLOL-GIIHNPQRSA-N
InChl CodeInChI=1S/C47H58N12O6/c1-27-34(33-15-7-9-17-37(33)54-27)23-41(58-44(62)35(49)22-31-25-51-26-53-31)45(63)55-28(2)43(61)57-40(21-30-24-52-36-16-8-6-14-32(30)36)47(65)59-39(20-29-12-4-3-5-13-29)46(64)56-38(42(50)60)18-10-11-19-48/h3-9,12-17,24-26,28,35,38-41,52,54H,10-11,18-23,48-49H2,1-2H3,(H2,50,60)(H,51,53)(H,55,63)(H,56,64)(H,57,61)(H,58,62)(H,59,65)/t28-,35-,38-,39+,40-,41+/m0/s1
SMILES CodeNCCCC[C@@H](C(N)=O)NC([C@@H](CC1=CC=CC=C1)NC([C@H](CC2=CNC3=C2C=CC=C3)NC([C@H](C)NC([C@@H](CC4=C(C)NC5=C4C=CC=C5)NC([C@H](CC6=CNC=N6)N)=O)=O)=O)=O)=O
References1) Mao Y, Tokudome T, Kishimoto I, Otani K, Miyazato M, Kangawa K. One dose of oral hexarelin protects chronic cardiac function after myocardial infarction. Peptides. 2014 Jun;56:156-62.

2) Mao Y, Tokudome T, Kishimoto I, Otani K, Hosoda H, Nagai C, Minamino N, Miyazato M, Kangawa K. Hexarelin treatment in male ghrelin knockout mice after myocardial infarction. Endocrinology. 2013 Oct;154(10):3847-54.

3) Xu X, Ding F, Pang J, Gao X, Xu RK, Hao W, Cao JM, Chen C. Chronic administration of hexarelin attenuates cardiac fibrosis in the spontaneously hypertensive rat. Am J Physiol Heart Circ Physiol. 2012 Sep 15;303(6):H703-11

More info

Potent, orally-active, centrally-penetrant, and highly selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue