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> Nuclear Receptor Ligands>Steroid Hormone Receptors>STX-64 (Irosustat )

Steroid Hormone Receptors

STX-64 View larger

STX-64 (Irosustat )

AOB5998

CAS No:288628-05-7

Chemical Name: STX64; Irosustat; BN83495; 667 Coumate; 6-Oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate

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$21.00

$21.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $17.85 Total: $89.25
110 $15.12 Total: $151.20
125 $12.81 Total: $320.25
150 $10.92 Total: $546.00
1100 $9.45 Total: $945.00

Data sheet

Molecular FormulaC14H15NO5S
Molecular Weight309.34
CAS Numbers288628-05-7
Storage Condition0°C (short term), -20°C (long term), desiccated
SolubilityDMSO
Purity98% by HPLC
SynonymSTX64; STX-64; STX 64; BN83495; BN-83495; BN 83495; STX 64667; STX64667; ST-64667; COUMATE. Irosustat.
IUPAC/Chemical Name6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate.
InChl KeyDSLPMJSGSBLWRE-UHFFFAOYSA-N
InChl CodeInChI=1S/C14H15NO5S/c15-21(17,18)20-9-6-7-11-10-4-2-1-3-5-12(10)14(16)19-13(11)8-9/h6-8H,1-5H2,(H2,15,17,18)
SMILES CodeO=S(OC1=CC(O2)=C(C=C1)C(CCCCC3)=C3C2=O)(N)=O
References1) Purohit A, et al. In vivo inhibition of estrone sulfatase activity and growth of nitrosomethylurea-induced mammary tumors by 667 COUMATE. Cancer Res. 2000 Jul 1;60(13):3394-6.

2) Raobaikady B, et al. Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate. J Steroid Biochem Mol Biol. 2003 Feb;84(2-3):351-8.

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A potent, irreversible inhibitor of steroid sulfatase.

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