Steroid Hormone Receptors

AC-186 View larger

AC-186

AT26537

CAS 1421854-16-1

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$38.00

$38.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $17.10 Total: $1,710.00
150 $19.76 Total: $988.00
125 $23.18 Total: $579.50
110 $27.36 Total: $273.60
15 $32.30 Total: $161.50

Data sheet

Molecular FormulaC18H17F3O
Molecular Weight306.32
CAS Numbers1421854-16-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeFC=1C=CC=CC1C2(C3=CC=C(O)C=C3)CCC(F)(F)CC2
ReferencesMcFarland K, et al. AC-186, a selective nonsteroidal estrogen receptor ? agonist, shows gender specific neuroprotection in a Parkinson's disease rat model. ACS Chem Neurosci. 2013 Sep 18;4[9] 1249-55.

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AC-186 is a nonsteroidal estrogen receptor ? (ER?) agonist with different affinities for ER? and ER?, with an EC50 of 6 nM for ER? and 5000 nM for ER?. AC-186 has neuroprotective activity and has been used in the study of Parkinson's disease.