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View larger BMS-986365
AT84297
CAS 2446928-30-7
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $139.40 | Total: $697.00 |
| 1 | 10 | $118.08 | Total: $1,180.80 |
| 1 | 25 | $100.04 | Total: $2,501.00 |
| 1 | 50 | $85.28 | Total: $4,264.00 |
| 1 | 100 | $73.80 | Total: $7,380.00 |
Data sheet
| Molecular Formula | C41H45F3N8O5S |
| Molecular Weight | 818.91 |
| CAS Numbers | 2446928-30-7 |
| Storage Condition | 0C Short Term, -20C Long Term |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | S=C1N(C(=O)C(C)(C)N1C2=CC(CC)=C(OCCN3C[C@@H](C)N(CC(NC4=CC(NC5C(=O)NC(=O)CC5)=CC=C4)=O)CC3)C=C2)C6=CC(C(F)(F)F)=C(C#N)C=C6 |
| References | Xu S, et al. Abstract ND02 Discovery of BMS-986365, a ligand-directed androgen receptor degrader [AR LDD] with a dual mechanism-of-action and best-in-class potential, for the treatment of advanced prostate cancer[J]. Cancer Research, 2024, 84[7_Supplement] ND02-ND02. |
More info
BMS-986365 (CC-94676) is an orally available, selective and highly potent AR degrader with potential anticancer activity that inhibits AR signaling and suppresses tumor growth for the study of prostate cancer.