Steroid Hormone Receptors

Ingenol mebutate View larger

Ingenol mebutate

ATN1047

CAS 75567-37-2

More details

Molarity Calculation Cart®

HOW TO ORDER

$54.00

$54.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $24.30 Total: $2,430.00
150 $28.08 Total: $1,404.00
125 $32.94 Total: $823.50
110 $38.88 Total: $388.80
15 $45.90 Total: $229.50

Data sheet

Molecular FormulaC25H34O6
Molecular Weight430.53
CAS Numbers75567-37-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCC=C(C)C(=O)O[C@H]1C(C)=C[C@@]23[C@H](C)C[C@@H]4[C@H]([C@H](C=C(CO)[C@@H](O)[C@]12O)C3=O)C4(C)C
ReferencesGhoul A, et al. Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. Cancer Res. 2009 May 15;69[10] 4260-9.

More info

Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-?, PKC-?, PKC-?, PKC-?, and PKC-? with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory and antitumor activity.