Steroid Hormone Receptors

TC-G 1005 View larger

TC-G 1005

AT8818

CAS 1415407-60-1

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$26.00

$26.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $11.70 Total: $1,170.00
150 $13.52 Total: $676.00
125 $15.86 Total: $396.50
110 $18.72 Total: $187.20
15 $22.10 Total: $110.50

Data sheet

Molecular FormulaC25H25N3O2
Molecular Weight399.48
CAS Numbers1415407-60-1
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES CodeCc1ccc(C)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc23)c1
ReferencesUrso A , D'Ovidio F , Xu D , et al. Bile acids inhibit cholinergic constriction in proximal and peripheral airways from humans and rodents[J]. AJP Lung Cellular and Molecular Physiology, 2019, 318[2].

More info

TC-G 1005 is a potent and selective GPBA agonist (EC50 :0.72 nM; hTGR5). Selective for TGR5 over FXR (farnesoid X receptor). Increases plasma GLP-1 levels and reduces blood glucose in mice. Orally available.