Steroid Hormone Receptors

AMG 837 calcium hydrate View larger

AMG 837 calcium hydrate

ATQ0020

CAS 1259389-38-2

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$31.00

$31.00 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
1100 $13.95 Total: $1,395.00
150 $16.12 Total: $806.00
125 $18.91 Total: $472.75
110 $22.32 Total: $223.20
15 $26.35 Total: $131.75

Data sheet

Molecular FormulaC52H44CaF6O8
Molecular Weight950.97
CAS Numbers1259389-38-2
Storage Condition0C Short Term, -20C Long Term
SolubilityDMSO
Purity98% by HPLC
SMILES Code[H]O[H].[H]O[H].O=C([O-])C[C@H](C#CC)C1=CC=C(OCC2=CC(C3=CC=C(C(F)(F)F)C=C3)=CC=C2)C=C1.O=C([O-])C[C@H](C#CC)C4=CC=C(OCC5=CC(C6=CC=C(C(F)(F)F)C=C6)=CC=C5)C=C4.[Ca+2]
ReferencesHouze JB, et al. AMG 837 a potent, orally bioavailable GPR40 agonist. Bioorg Med Chem Lett. 2012 Jan 15;22[2] 1267-70.

More info

AMG 837 calcium hydrate, a potent GPR40 agonist with an EC50 of 13 nM, exhibits high selectivity over GPR41, GPR43, and GPR120 (EC50 > 10,000 nM).