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Zoledronic Acid
AOB9799
CAS: 118072-93-8
Chemical Name: Zoledronate; Zometa; Reclast; Aclasta; (1-Hydroxy-2-imidazol-1-yl-1-phosphonoethyl)phosphonic acid
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 100 | $4.05 | Total: $405.00 |
| 1 | 50 | $4.68 | Total: $234.00 |
| 1 | 25 | $5.49 | Total: $137.25 |
| 1 | 10 | $6.48 | Total: $64.80 |
| 1 | 5 | $7.65 | Total: $38.25 |
Data sheet
| Molecular Formula | C5H10N2O7P2 |
| Molecular Weight | 687.40 |
| CAS Numbers | 118072-93-8 |
| Storage Condition | 0°C (short term), -20°C (long term), desiccated |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| Synonym | Zometa |
| IUPAC/Chemical Name | [1-Hydroxy-2-(1H-imidazol-1-yl)ethylidene]bisphosphonic acid |
| InChl Key | XRASPMIURGNCCH-UHFFFAOYSA-N |
| SMILES Code | OC(P(O)(O)=O)(P(O)(O)=O)CN1C=CN=C1 |
| References | 1) Schech et al (2013) Zoledronic acid reverses the epithelial-mesenchymal transition and inhibits self-renewal of breast cancer cells through inactivation of NF-κB. Mol.Cancer Ther. 12 1356 PMID: 23619300 2) Tassone et al (2003) Zoledronic acid induces antiproliferative and apoptotic effects in human pancreatic cancer cells in vitro. Br.J.Cancer 88 1971 PMID: 12799645 |
| PubChem ID | 68740 |
More info
Inhibitor of farnesyl pyrophosphate (diphosphate) synthase, preventing protein prenylation within the mevalonate pathway and leading to the induction of apoptosis and eventually, osteoclast-cell death